منابع مشابه
A Review on Solubility Enhancement Using Hydrotropic Phenomena
Solubilization of poorly water-soluble drugs has been a very important issue in screening studies of new chemical entities as well as formulation research. Various techniques are employed to enhance the aqueous solubility of poorly water-soluble drugs and hydrotropic solubilisation is one of them. A hydrotrope is a compound that solubilises hydrophobic compounds in aqueous solution. The problem...
متن کاملHydrotropic dendrimers of generations 4 and 5: synthesis, characterization, and hydrotropic solubilization of paclitaxel.
Polyglycerol dendrimers (PGDs) with 4-5 generations were synthesized and used to investigate the effect of dendritic architecture and its generation on aqueous solubilization of paclitaxel (PTX), a poorly water-soluble drug. Chemical and physical properties of the PGDs were characterized by NMR, MALDI-TOF mass, GPC, viscosity, and dynamic light scattering measurements. The PTX solubility in all...
متن کاملHydrotropic solubilization of poorly water-soluble drugs.
The solubilizing ability of two aromatic hydrotropes, N,N-diethylnicotinamide (DENA) and N,N-dimethylbenzamide (DMBA), was investigated using a set of 13 poorly soluble, structurally diverse drugs. The number of aromatic rings in the solute molecule has a very strong effect on the solubility enhancement produced by either hydrotrope. However, although solubility enhancements in the order of 100...
متن کاملOn the Informational Requirements of Indian Cooking
This short note is inspired by Prof. S. K. Mitter’s comments on the informational requirements of Indian cooking, made in response to Prof. D. Shah’s “Salt Lemma” on September 20. It casts cooking as a problem of controlling a dynamical system; the system may be stable or unstable (depending on the cook and the food being cooked). It discusses a scenario where there is a local actuator/observer...
متن کاملObservations on "Tinning" Cooking Pots in India
sufficient coating of tin being applied, or to the cooks cleaning the surface of the utensils with sand and thus laying bare the copper. The result is probably a committee, which either throws the blame on the cooks or the tinning contractor, and causes much trouble to the regimental authorities and the commissariat department A short time ago when inspecting the hospital cooking utensils which...
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ژورنال
عنوان ژورنال: JAPAN TAPPI JOURNAL
سال: 1971
ISSN: 0022-815X,1881-1000
DOI: 10.2524/jtappij.25.18